Biochemist Jessie Inchauspe heads into work one morning at a genetics lab in California. During the morning meeting, management offer staff the chance to self-test a new medical device. Jessie accepts.

She couldn’t have known this device would take her on a journey of discovery to reshape her health and help countless others do the same.

The device was a continuous blood sugar monitor, and it was this, combined with her academic background, and a remarkable willingness to use herself as a lab rat, that began a journey of discovery into how blood sugar affects our health.

In today’s episode, Jonathan is joined by two leading experts on the topic:

Jessie Inchauspe is a biochemist, bestselling author, and founder of the Glucose Goddess movement who’s helped hundreds of thousands of people improve their health by making cutting-edge science accessible.
Dr. Sarah Berry is one of the world's leading experts on human nutrition, who has personally run over 20 randomized clinical trials looking at how humans respond to different fats.

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Antibiotics are one of the greatest discoveries of the 21st century. Since their inception, they’ve saved countless lives, but these miracle drugs come at a cost. In some cases, they can seriously affect your health or can even be life-threatening.

In today’s episode, Jonathan puts himself under the microscope. After an injury forced him to take antibiotics, he shows you the effect they had on his own gut bacteria.

Jonathan’s joined by Dr. Will Bulsiewicz and Prof. Tim Spector, who explore the impact of different types of antibiotics, how they affect your bacteria in the short and long term, and how we can reverse the unwanted effect of these drugs.

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What does "organic" food mean? And how do you know if something's organic?

Of course, foods tell you if they're organic in massive letters on the packaging. And they cost way more. But what makes food organic? Is eating organic better for your health? And are the benefits worth the expense?

Luckily, Professor Tim Spector is here today with answers. Tim is one of the world's top 100 most cited scientists, a scientific co-founder of ZOE, and the author of the bestselling book Food for Life: The New Science of Eating Well.

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Our bodies naturally follow a roughly 24-hour cycle, called our circadian rhythm. And every cell has a rhythm.

As we get older, we tend to lose muscle, making us more prone to falls and less able to live independently. Though we can't stop aging, staying active helps keep our muscles strong and our bodies healthy for longer.

Prof. Karyn Esser is a specialist in how the body's natural rhythms affect muscles. Today, she guides us through the latest research and shows that it's always possible to harness the power of your muscles to enhance your quality of life. She is a professor in the Department of Physiology and Aging at the University of Florida, where she’s also the co-director of the University of Florida Older Americans Independence Center.

In today's episode of ZOE Science & Nutrition, Jonathan and Karyn explore the body's internal clocks and ask: why do our muscles have their own schedule, and is there an ideal time of day to exercise?

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Did you know that every 12 years, our skeletons undergo a complete transformation?

Osteoporosis, a condition where bones become fragile, significantly increases the risk of fractures from minor incidents, often without any noticeable symptoms. Worldwide, it affects one in three women and one in five men over fifty, leading to pain, potential disability and loss of independence.

In today’s episode, Jonathan, Tim and Cyrus ask the question: How can understanding osteoporosis and implementing targeted lifestyle changes enhance bone health and reduce the risk of fractures?

Cyrus Cooper is a Professor of Rheumatology at the University of Southampton, where he is also the Director of the MRC Lifecourse Epidemiology Unit and Vice-Dean of Medicine. In addition, he’s a Professor of Musculoskeletal Science at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences at the University of Oxford.

Tim Spector is one of the world’s top 100 most-cited scientists, a professor of epidemiology, and scientific Co-Founder at ZOE. Tim trained originally in rheumatology and epidemiology.

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Have you gained weight in lockdown? How many pounds have Americans gained on average? Professor Tim Spector and Emily Leeming, RDN share learnings from over 97,000 US respondents on whether or not Americans have gained weight during lockdown and if they have, why. Tim and Emily discuss the science of snacking, how to lose weight by getting your biology on your side and how to test your biology with ZOE.

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"What I really like about the ZOE approach is that it's not a kind of restrictive list of do's and don'ts and things you're not supposed to eat. It's all about adding in the good stuff."

We’ve teamed up with Hugh Fearnley-Whittingstall to bring you seasonal recipes that pack in the plants to support your gut health.

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Interested in understanding how many carbs to eat on keto or paleo? Are you trying to decide if low-carb or low-fat is better for you?

Christopher Gardner Professor of Medicine at Stanford University, talks about the DIETFITS study, different diets, the science behind them, and how many carbs you should really eat. He discusses randomized control trials and what the future looks like for personal nutrition.

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Watch our simple steps to log your vaccine with the ZOE COVID Symptom Study.

To log your vaccine, open the ZOE COVID Symptom Study app and begin your daily report.

You should be presented with a screen titled, ‘Your COVID-19 vaccines’ - if you don’t see this screen, head to the app store and make sure you’ve got the latest version of the app installed on your device.

Pick the name of the vaccine you received from the drop down list.

And select the date of your dose from the calendar.

Enter the batch number of your vaccine if you know it. You’ll find details on a card given to you at the time you were vaccinated.

Once you’ve completed these steps, you’ll see your vaccine record.

You can edit these details, add a second dose or simply confirm your details are correct.

The app will then ask questions about any local after effects you might be experiencing around the injection site.

Once you’ve completed this step, you can begin the usual symptom report.

If you’re not feeling quite right, whether or not symptoms could be a result of your vaccine, tell us about it.

If you reported any of the symptoms associated with COVID-19 infection, even if they could have been brought on as an after effect of your vaccine, we’ll invite you for a COVID-19 test via email.

Even though you’ve been recently vaccinated, we recommend you accept any invitation to test yourself for COVID.

Remember, you’re still vulnerable to infection for some time after your vaccination, and should continue to take precautions and follow official guidance

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Asking Siri or ChatGPT for medical advice right now is a terrible idea. But major breakthroughs in AI and language processing are poised to revolutionize many industries, including medicine.

While our first fear is that AI will replace human jobs, Dr. Eric Topol is far more optimistic. The world-renown cardiologist and author has been studying how AI can free doctors from the administrative burdens of the medical business, spend more meaningful time discussing care with patients, and allow patients to self-diagnose far more accurately and efficiently.

But as with all emerging tech, the optimism must be balanced with risk. This week, Jonathan speaks with Dr. Topol about how your next visit to the clinic could be very different.

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Professor Tim Spector from the COVID Symptom Study and ZOE shares the latest data in the UK revealing mixed signals across the country. For the latest regional data visit covid.joinzoe.com/data

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How did two tech entrepreneurs bring one of the world's most-cited scientists on board to start a personalized nutrition company? By supporting him in conducting the world's largest nutrition science study.

Welcome to the ZOE nutrition revolution.

In this episode our co-founders, Professor Tim Spector OBE, Jonathan Wolf and George Hadjigeorgiou sit down to tell the ZOE story and their manifesto for the future of nutrition.

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This year, cases of an invasive bacterial infection are rising earlier than usual in the United States, the United Kingdom, and other countries across Europe.

Infection with group A Streptococcus bacteria — commonly known as strep A — usually only causes mild illness. However, things have become severe in some cases, with several children dying in recent weeks.

So, should we be worried? And what symptoms should we look out for to help us identify this illness in ourselves and our families?

In today’s episode, Jonathan is joined by a world-leading expert on the subject; Shiranee Sriskandan is a professor of infectious diseases at Imperial College London, and her research focuses specifically on strep A bacteria. Regular guest and ZOE co-founder Tim Spector also joins, and as one of the world’s top 100 most cited scientists, Tim has been closely following infectious diseases in the community through the ZOE Health Study.

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Should you be counting calories? We sat down with Christopher Gardner, Professor of Medicine at Stanford University, and Sarah Berry, reader in nutritional sciences at King's College London & lead researcher of the PREDICT studies, to find out.

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Doctors and clinical researchers Claire Steves and Tim Spector share an update on the insights they're learning from COVID Symptom Tracker and how we're using it to aid the global health community, slow the spread of the virus and identify those at risk sooner.

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Tim guides contributors step by step how to use the new improved health report feature in the ZOE Health Study app.

He goes through setting up your 'Usual Self' as well as how to log health reports from now, once your 'Usual Self' is in place.

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Dr Claire Steves and Professor Tim Spector delve into the latest data from the COVID Symptom Study. They will share data around those who have been hospitalised and factors that place them at risk. This includes lung disease, type 2 diabetes, lung disease, asthma, obesity and other co-morbidities.

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Professor Tim Spector and Jonathan Wolf discuss the current state of the UK and when we may be in a position to lift lockdown - as well as the risk of lifting it too early. They analyse the latest data from the 2.5 million contributors to the COVID Symptom Tracker showing the decrease in symptomatic COVID cases across the country.

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These tasty and simple-to-make blue muffins were developed by world-leading scientists as an easy and inexpensive way to test your gut. You can bake your own blue muffins at home and join the #bluepoopchallenge to learn about your gut health.

Visit https://bluepoopchallenge.com/ to find the recipe, learn more about the #bluepoopchallenge, and challenge friends and family to participate

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Welcome to 2023! Whether you partied the night away or went to bed early, we’re all in the same boat: a new year means thinking about new year’s resolutions.

This tradition dates back 4000 years, so it’s certainly stood the test of time. But are new year’s resolutions a good idea? Or simply a get way to set yourself up to fail?

Perhaps science has something to say about this. In this episode, Jonathan speaks with Tara Swart and Sarah Berry, who share techniques that will give you the best chance of sticking to your New Year’s resolutions. They also discuss whether these promises are a good idea in the first place.

Tara Swart is a medical doctor, a neuroscientist, and the author of The Source: Open Your Mind, Change Your Life. She also has her own podcast called Reinvent Yourself. Sarah Berry is one of the world's leading experts on human nutrition. She has personally run more than 20 randomized clinical trials examining how humans respond to different fats.

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"It turns out that my body handles fats poorly - something that had never been picked up by any fasting lab tests in the past...Using the ZOE food scores I was able to make some shifts in my dietary patterns to avoid overloading my fat handling capacity and hopefully ward off dietary inflammation in the long run. I came away feeling educated and empowered to eat a nourishing diet specialized to my metabolism."

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The ZOE Science and Nutrition podcast is finally here!

ZOE co-founder Jonathan Wolf will be chatting to the world’s leading experts to answer your questions on nutrition to help people like you improve their health.

We are starting off with not one, but TWO episodes we know you’ll love:

Episode 1: What’s the Story With Food Intolerances?
With Dr Will Bulsiewicz, ZOE’s U.S. Medical Director, board-certified gastroenterologist and New York Times best-selling author.

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Professor Tim Spector from the ZOE COVID Symptom Study app discusses the COVID Symptom Study app Schools Programme.

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Sugar sweetened beverages are everywhere. Some have misleading claims about being great for your health. So what’s the truth about the nutritional content of these sugary drinks, and are they ever healthy?

Jonathan talks with Professor Walter Willett to try and find out.

Professor Walter Willett, from the Harvard T. H. Chan School of Public Health, is the world's most cited nutritional scientist — with over 2,000 publications and several books to his name. Prof. Willett has focused much of his work over the last 40 years on the development and evaluation of methods to study the effects of diet on the occurrence of major diseases.

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As we age, we need to keep our muscles strong. How can we best achieve that, and potentially add years to our life?

Jonathan talks with Dr. Brad Schoenfeld to try and find out.

Dr. Schoenfeld is a professor at Lehman College in New York City. His research focuses on muscle adaptations to strength training. He's published over 300 studies in the field of exercise and sports nutrition as a scientist and began his career as a competitive bodybuilder and personal trainer.

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